C181 - Treatment of Pediatric Multiple Sclerosis in the Current Era
| Event Time: | Wednesday May 8, 2019 1:00 pm to 3:00 pm |
| Topic(s): | Child Neurology and Developmental Neurology, MS and CNS Inflammatory Disease |
| Director(s): | Brenda Banwell MD, FAAN |
| Description: | This program will focus on recent advances in the care of children and teens with multiple sclerosis. Faculty will first review the 2017 diagnostric criteria for MS, outlining how these criteria apply in the pediatric MS context. The emerging recognition of myelin oligodendrocyte glycoprotein (MOG) antibodies in identifying pediatric patients with a non-MS clinical course will be highlighted. Following discussion regarding accurate diagnosis, faculty will then focus on treatment. The recent PARADIGMS trial, the first large-scale randomized clinical trial in pediatric MS, will be reviewed. An overview of ongoing clinical trials will be presented. An approach to clinical care will be demonstrated, including dosing and safety monitoring considerations. Finally, faculty will synthesize the current treatment landscape with discussion centered on strategies for early, effective, and evidence-based care for pediatric MS. |
| Completion Message: | Attendees should feel competent in the approach to diagnosis of MS in children; will be provided with strategies to investigate disorders considered in the differential, in order to meet the requirement of "excluding other diagnoses" prior to conferring the diagnosis of MS; be able to discuss up-to-date information regarding currently available therapeutic agents for pediatric MS, including dosing and safety monitoring; and be informed regarding upcoming clinical trials for pediatric MS. |
| CME Credits: | 2 |
| Core Competencies: | Patient Care, Medical Knowledge, Practice-Based Learning and Improvement |
| Start/End Time | Title | Faculty |
|---|---|---|
| 1:00 PM - 1:05 PM | Introduction and Welcome | Brenda Banwell MD, FAAN |
| 1:05 PM - 1:45 PM | Diagnosis of Pediatric MS: Considerations of Treatment Selection | Brenda Banwell MD, FAAN |
| 1:45 PM - 2:15 PM | PARADIGMS Trial: Implications for Pediatric MS | Tanuja Chitnis MD, FAAN |
| 2:15 PM - 2:45 PM | Upcoming Clinical Trials in Pediatric MS | Emmanuelle Waubant MD, PhD, FAAN |
| 2:45 PM - 3:00 PM | Audience Discussion | Brenda Banwell MD, FAAN, Tanuja Chitnis MD, FAAN, Emmanuelle Waubant MD, PhD, FAAN |
| Speaker | Disclosure |
|---|---|
| Brenda Banwell, MD, FAAN | Dr. Banwell has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Novartis. |
| Tanuja Chitnis, MD, FAAN | Dr. Chitnis has received personal compensation for advisory boards/consulting with F. Hoffman-La Roche, Biogen and Novartis. Dr Chitnis has received research support from Biogen, Merck Serono, Verily and Novartis. |
| Emmanuelle Waubant, MD, PhD, FAAN | Dr. Waubant has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with AAN for Frontiers in neurology talk, The Corpus for talks, compensation for editorial work for Annals of Clinical and Translational Neurology and MS and Related Disorders. Site PI for clinical trials with Roche, Biogen Idec and Novartis |
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