C181 - Treatment of Pediatric Multiple Sclerosis in the Current Era

Event Time: Wednesday May 8, 2019 1:00 pm to 3:00 pm
Topic(s): Child Neurology and Developmental Neurology, MS and CNS Inflammatory Disease
Director(s): Brenda Banwell MD, FAAN
Description: This program will focus on recent advances in the care of children and teens with multiple sclerosis. Faculty will first review the 2017 diagnostric criteria for MS, outlining how these criteria apply in the pediatric MS context. The emerging recognition of myelin oligodendrocyte glycoprotein (MOG) antibodies in identifying pediatric patients with a non-MS clinical course will be highlighted. Following discussion regarding accurate diagnosis, faculty will then focus on treatment. The recent PARADIGMS trial, the first large-scale randomized clinical trial in pediatric MS, will be reviewed. An overview of ongoing clinical trials will be presented. An approach to clinical care will be demonstrated, including dosing and safety monitoring considerations. Finally, faculty will synthesize the current treatment landscape with discussion centered on strategies for early, effective, and evidence