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C160 - Autoimmune Neurology II Advanced: Autoimmune Encephalitis at the Frontiers of Neuroscience

Event Time:	Tuesday May 7, 2019 3:30 pm to 5:30 pm
Topic(s):	Neurohospitalist, Autoimmune Neurology, MS and CNS Inflammatory Disease
Director(s):	Eoin Flanagan MBBCh
Description:	Recent years have been very exciting for autoimmune neurology: many new diseases have been discovered, providing possibilities to treat patients previously considered untreatable. Faculty will describe the approach to autoimmune encephalitis diagnosis including diagnostic pearls and pitfalls of antibody testing. We will review treatments for the different types of autoimmune encephalitis including those for diseases associated with antibodies to cell surface markers and those to intracellular antigens. There will be a particular focus on autoimmune epilepsy and how to recognize it. We will discuss how autoimmune encephalitis is increasingly being encountered in novel settings such as post CNS infections (post-HSV encephalitis), after medication use (e.g., immune-checkpoint inhibition), and post-transplant. This program complements Autoimmune Neurology I Basics and Beyond: Autoimmune Encephalitis and Paraneoplastic Neurological Syndromes of the CNS and PNS, but covers independent topics.
Completion Message:	Participants should be able to understand the autoantibody nomenclature, recognize autoimmune neurologic disorders occuring in novel settings, know the neurologic and cancer associations of the autoantibodies, know the pitfalls in antibody testing, know the appropriate oncological evaluations for paraneoplastic neurologic disorders, understand how to diagnose and treat autoimmune epilepsy, and know some treatment regimens for autoimmune neurologic disorders.
CME Credits:	2
Core Competencies:	Patient Care, Medical Knowledge

Program Speakers - Tentative
Start/End Time	Title	Faculty
3:30 PM - 3:35 PM	Introduction	Eoin P. Flanagan MBBCh
3:35 PM - 4:10 PM	Diagnostic Approach to Autoimmune Encephalitis	Eoin P. Flanagan MBBCh
4:10 PM - 4:45 PM	Autoimmune Epilepsy: From Faciobrachial Dystonic Seizures to Status Epilepticus	Sarosh Irani MD, PhD
4:45 PM - 5:20 PM	The Expanding Spectrum of Autoimmune Encephalitis Beyond Paraneoplastic Disease	Jenny Linnoila MD, PhD
5:20 PM - 5:30 PM	Questions and Answers and Closing Remarks	Faculty

Disclosures
Speaker	Disclosure
Eoin P. Flanagan, MBBCh	Dr. Flanagan has received research support from Medimmune.
Sarosh Irani, MD, PhD	Dr. Irani has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with MedImmune and ADCT. Dr. Irani has received royalty, license fees, or contractual rights payments from LGI1, CASPR2 and contactin-2, licenced to Euroimmun Ltd. He receives royalties from the patent. Dr. Irani has received research support from UCB Pharma and ONO for immunology research.
Jenny Linnoila, MD, PhD	Dr. Linnoila has nothing to disclose.

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