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N2 - Neuroscience in the Clinic: Child Neurology: Neurologic Disorder Through a Lifespan- A Focus on MS

Event Time: Sunday April 23, 2017 3:30 pm to 5:30 pm
Topic(s): Child Neurology and Developmental Neurology
Director(s): Shafali Jeste MD, Rebecca Lehman MD
Description: The onset of Multiple Sclerosis (MS) most commonly occurs in young adults, but onset may also occur in children and in the elderly. Pathological features include both focal demyelination, inflammation, neuronal and axonal loss, as well as a more global loss of central nervous system tissue integrity. Cognitive impairment is a major source of morbidity for patients with MS, but cognitive sequelae vary by age. In this course, we will take a "life-span" approach to the clinical, neurobiologic, and radiographic aspects of cognitive impairment in MS. This course will provide up-to-date information for all clinicians caring for patients with MS and will foster discourse between pediatric and adult neurologists.
Completion Message: The foremost goal of this course is to bring the neurology community together to consider the impact of MS on cognitive function- a key patient-centered outcome. Attendees will gain insight into the biological underpinings of cognitive performance in MS with a focus on MS in the maturing, mature, and senescent CNS.
CME Credits: 2
Core Competencies: Medical Knowledge, Patient Care, Systems-Based Practice

Program Speakers - Tentative

Start/End Time Title Faculty
3:30 PM - 3:35 PM Case Report: Pediatric MS Patient Story Outlining Cognitive Changes Maria Amato PhD 
3:35 PM - 3:40 PM Case Report: Elderly Adult MS Patient Story Outlining Changes Over Time in Cognition Lauren Krupp MD, FAAN 
3:40 PM - 3:50 PM Neuropsychological and MRI Features of Cognitive Impairment in Youth with MS Christine Till PhD 
3:50 PM - 4:00 PM Neuropsychological and MRI Features of Cognitive Impairment in Elderly with MS Lauren Krupp MD, FAAN 
4:00 PM - 4:10 PM Management of Cognitive Impairment in Pediatric MS Patients Brenda Banwell MD, FAAN 
4:10 PM - 4:20 PM Management of Cognitive Impairment in Elderly MS Patients Lauren Krupp MD, FAAN 
4:20 PM - 4:35 PM N2.001: Risks of psychiatric disorders in children and young adults with demyelinating diseases of the central nervous system: a national record-linkage study Julia Pakpoor MBBS 
4:35 PM - 4:50 PM N2.002: Structural Connectivity Abnormalities Underlying Cognitive Impairment in Pediatric Multiple Sclerosis Ermelinda De Meo  
4:50 PM - 5:30 PM Panel Discussion: Emerging Studies, Role of Current Therapies, Consideration of NEDA (No Evidence of Disease Activity, and the Concept of Cognitive Rehabilitation) Faculty 

Disclosures

Speaker Disclosure
Maria Pia Amato, PhD Dr. Amato has received personal compensation for activities with Biogen Idec, Merk Serono, Bayer, Novartis, Teva, Sanofi, Genzyme, and Almirall.

Brenda Banwell, MD, FAAN Dr. Banwell has nothing to disclose.

Ermelinda De Meo Dr. De Meo has nothing to disclose.

Lauren B. Krupp, MD, FAAN Pfizer - DSMB, Sanofi-Aventis: DSMB, Novartis: consultation, Redhill pharmaceutical: consulting. Royalty payments for fatigue scale: Abbvie, Eisai, Amicus, RESMED, Janseen, Merck. Biogen: quantitative outcome measures in clinical practice Novartis: Effects of mindfulness on clinical outcomes.

Julia Pakpoor, MBBS Dr. Pakpoor has nothing to disclose.

Christine Till, PhD Dr. Till has nothing to disclose.

Abstract Presenters

Start Time Pub. Title Presenter
4:20 PM 001 Risks of psychiatric disorders in children and young adults with demyelinating diseases of the central nervous system: a national record-linkage study Julia Pakpoor, MBBS
Disclosure:
Dr. Pakpoor has nothing to disclose.

4:35 PM 002 Structural Connectivity Abnormalities Underlying Cognitive Impairment in Pediatric Multiple Sclerosis Ermelinda De Meo
Disclosure:
Dr. De Meo has nothing to disclose.

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