Clinical Decision Making After the Dust Settles on Clinical Trials

Event Time: Wednesday April 30, 2014 2:00 pm to 6:00 pm
Topic(s): General Neurology, Research Methodology, Education, and History
Director(s): Barbara Vickrey MD, MPH, FAAN, Linda Williams MD, FAAN
Description: Once a trial establishing the efficacy of a new treatment is published, many questions remain to be answered before a neurologist in practice can apply that new knowledge in a way to produce the full health benefit for individual patients and across that neurologist's entire practice. "Outcomes research" encompasses a broad range of topics that are intended to fill the gap between clinical trial findings and improved health of patients under physicians' care. In this session, research in 4 key areas that are critical to consider - once the "dust settles" on a randomized clinical trial publication - are illustrated, and the current status of each of these areas in neurology is summarized. These 4 key areas are (1) effectiveness, or to what extent the benefits and risks of the new treatment are similar in a “real world” practice setting rather than a clinical trial; (2) decision support, or approaches utilizing technology and building on the science of decision-making and cognitive psychology, to help neurologists apply complex clinical trial findings appropriately and fully; (3) incorporation of patient preferences in decisions about new treatments, particularly relevant for treatments for which there are risks and benefits that involve tradeoffs on which the patient must weigh in to make sure that treatment decisions yield the best outcomes; and (4) implementation of a new intervention, including coordinated care delivery models, where the context of care and the methods of implementing an intervention in a given practice setting may impact patient outcomes. Opportunities for neurologists in academic and private practice to shape this research agenda and participate in "field" work will be highlighted.
Completion Message:
CME Credits: 4
Core Competencies:

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